Long-term outcomes of free internal limiting membrane transplant for unclosed macular holes after extensive internal limiting membrane peeling and silicone oil tamponade: a report of two cases
Keywords:ILM graft, macular hole, unclosed
We report the long-term outcome of two cases of free internal limiting membrane (ILM) transplant for unclosed macular holes after extensive internal limiting membrane peeling and silicone oil tamponade. Free ILM graft was harvested and then successfully tucked against the inner edges of the macular hole in two eyes. All macular holes closed. In one case, the ILM filled the macular hole 100% in all meridians and remained closed 7 years after surgery. In another case, the ILM filled the gap of the macular hole 100% in the horizontal meridian and approximately 70% in the vertical meridian and re-opened 5 weeks after surgery. Filling the entire macular hole area with the ILM graft may improve long-term anatomical outcomes.
Kwok AK, Lai TY, Wong VW. Idiopathic macular hole surgery in Chinese patients: a randomised study to compare indocyanine green-assisted internal limiting membrane peeling with no internal limiting membrane peeling. Hong Kong Med J 2005;11:259-66.
Spiteri Cornish K, Lois N, Scott NW, et al. Vitrectomy with internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole. Ophthalmology 2014;121:649-55.
Iezzi R, Kapoor KG. No face-down positioning and broad internal limiting membrane peeling in the surgical repair of idiopathic macular holes. Ophthalmology 2013;120:1998-
Michalewska Z, Michalewski J, Adelman RA, Nawrocki J. Inverted internal limiting membrane flap technique for large macular holes. Ophthalmology 2010;117:2018-25.
Morizane Y, Shiraga F, Kimura S, et al. Autologous transplantation of the internal limiting membrane for refractory macular holes. Am J Ophthalmol 2014;157:861-9.
Ra H, Lee WK. Contralateral autologous internal limiting membrane transplantation for closure of a refractory macular hole: surgical technique. Ophthalmic Surg Lasers Imaging Retina 2018;49:e75-e77.
Ding C, Li S, Zeng J. Autologous neurosensory retinal transplantation for unclosed and large macular holes. Ophthalmic Res 2019;61:88-93.
Chen SN, Yang CM. Lens capsular flap transplantation in the management of refractory macular hole from multiple etiologies. Retina 2016;36:163-70.
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