Latanoprost for the prevention of ocular hypertension after neodymium:yttrium-aluminumgarnet laser posterior capsulotomy

Abstract

Aim: To evaluate the efficacy of latanoprost for the prevention of ocular hypertension after neodymium: yttrium-aluminum-garnet laser posterior capsulotomy.

Methods: Fifty six eyes of 56 consecutive patients receiving neodymium:yttrium-aluminum-garnet laser capsulotomy for posterior capsule opacification were randomized to group 1, who received 1 drop of latanoprost 0.005%, or to group 2, who received 1 drop of normal saline, 1 hour before the laser treatment. Intraocular pressures were taken before instillation of the eye drop, and at 1 hour and 2 hours after the laser procedure. Student’s t-test was used to analyze the differences in intraocular pressures between the 2 groups.

Results: There were no statistically significant changes in the mean intraocular pressures of the 2 groups at 1 and 2 hours after neodymium:yttrium-aluminum-garnet laser capsulotomy compared with the baseline. There was no statistically significant difference in the mean intra- ocular pressures between the 2 groups at the same time intervals.

Conclusions: A single application of latanoprost given 1 hour before neodymium:yttrium-aluminum-garnet laser posterior capsulotomy did not produce a statis- tically significant intraocular pressure lowering effect during the first 2 hours after the laser procedure when compared with a control group.