Update on photodynamic therapy with verteporfin for macular diseases

Authors

  • Wai-man Chan Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • David TL Liu Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Timothy YY Lai Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Kenneth KW Li Department of Ophthalmology and Visual Sciences, United Christian Hospital, Kowloon, Hong Kong, China.
  • Vicent YW Lee Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Chi-wai Tsang Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Wico WK Lai Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Henry HW Lau Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Emily WH Tang Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Shaheeda Mohamed Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Etrian Lim Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Dennis SC Lam Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

Abstract

Choroidal neovascularization in the macula is a major cause of visual disability in developed countries. Age-related macular degeneration is one of the commonest underlying etiologies for choroidal neovascularization, while other conditions include pathologic myopia, idiopathic, post- choroiditis, iatrogenic, and other causes. There have been no good and safe treatments for choroidal neovascularization at subfoveal areas. Photodynamic therapy with verteporfin has been shown to be effective in reducing the likelihood of visual loss due to choroidal neovascularization in age-related macular degeneration, especially when the lesion has predominantly classic composition. Further evidence indicates the beneficial effects in age- related macular degeneration with progressive occult choroidal neovascularization of small size and also in subfoveal choroidal neovascularization of pathologic myopia. The indications and applications of photodynamic therapy have been expanding swiftly and this treatment modality may provide a new hope for diseases such as polypoidal choroidal vasculopathy and central serous chorioretino- pathy, which are more prevalent in Asian populations.

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Published

2004-12-01

How to Cite

1.
Chan W- man, Liu DT, Lai TY, Li KK, Lee VY, Tsang C- wai, Lai WW, Lau HH, Tang EW, Mohamed S, Lim E, Lam DS. Update on photodynamic therapy with verteporfin for macular diseases. Hong Kong J Ophthalmol [Internet]. 2004Dec.1 [cited 2022Aug.13];8(1):23-35. Available from: https://hkjo.hk/index.php/hkjo/article/view/95

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Section

Review Articles