Antithrombotic treatment in ophthalmic surgery


  • Tommy CY Chan Department of Ophthalmology, Hong Kong Sanatorium and Hospital, Hong Kong
  • Alex LC Tam Faculty of Medicine, University of Toronto, Canada
  • Victoria WY Wong Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong
  • Ben NM Lam Hong Kong Eye Hospital, Hong Kong


Rossini R, Capodanno D, Lettieri C, et al. Prevalence, predictors, and long-term prognosis of premature discontinuation of oral antiplatelet therapy after drug eluting stent implantation. Am J Cardiol 2011;107:186-94.

Katz J, Feldman MA, Bass EB, et al. Risks and benefits of anticoagulant and antiplatelet medication use before cataract surgery. Ophthalmology 2003;110:1784-8.

Kobayashi H. Evaluation of the need to discontinue antiplatelet and anticoagulant medications before cataract surgery. J Cataract Refract Surg 2010;36:1115-9.

Barequet IS, Sachs D, Shenkman B, et al. Risk assessment of simple phacoemulsification in patients on combined anticoagulant and antiplatelet therapy. J Cataract Refract Surg 2011;37:1434-8.

Cheung JJC, Liu S, Li KKW. Phacoemulsification cataract surgery in patients receiving novel oral anticoagulant medications. Int Ophthalmol 2018 Feb 13 [Epub ahead of print]

Narendran N, Williamson TH. The effects of aspirin and warfarin therapy on haemorrhage in vitreoretinal surgery. Acta Ophthalmol Scand 2003;81:38-40.

Fu AD, McDonald HR, Williams DF, et al. Anticoagulation with warfarin in vitreoretinal surgery. Retina 2007;27:290-5.

Dayani PN, Grand MG. Maintenance of warfarin anticoagulation for patients undergoing vitreoretinal surgery. Arch Ophthalmol 2006;124:1558-65.

Sun MT, Wood MK, Chan W, et al. Risk of intraocular bleeding with novel oral anticoagulants compared with warfarin: a systematic review and meta-analysis. JAMA Ophthalmol 2017;135:864-70.

Olson JM, Scott IU, Kerchner DL, et al. Association between systemic anticoagulation and rate of intraocular hemorrhage following intravitreal anti-VEGF therapy for age-related macular degeneration. Ophthalmic Surg Lasers Imaging Retina 2013;44:455-9.

Mason JO 3rd, Frederick PA, Neimkin MG, et al. Incidence of hemorrhagic complications after intravitreal bevacizumab (avastin) or ranibizumab (lucentis) injections on systemically anticoagulated patients. Retina 2010;30:1386-9.

Dayani PN, Siddiqi OK, Holekamp NM. Safety of intravitreal injections in patients receiving warfarin anticoagulation. Am J Ophthalmol 2007;144:451-3.

Cobb CJ, Chakrabarti S, Chadha V, et al. The effect of aspirin and warfarin therapy in trabeculectomy. Eye (Lond) 2007;21:598-603.

Law SK, Song BJ, Yu F, et al. Hemorrhagic complications from glaucoma surgery in patients on anticoagulation therapy or antiplatelet therapy. Am J Ophthalmol 2008;145:736-46.

Custer PL, Trinkaus KM. Hemorrhagic complications of oculoplastic surgery. Ophthal Plast Reconstr Surg 2002;18:409-15.

Kent TL, Custer PL. Bleeding complications in both anticoagulated and nonanticoagulated surgical patients. Ophthal Plast Reconstr Surg 2013;29:113-7.

Parkin B, Manners R. Aspirin and warfarin therapy in oculoplastic surgery. Br J Ophthalmol 2000;84:1426-7.

Spyropoulos AC, Douketis JD. How I treat anticoagulated patients undergoing an elective procedure or surgery. Blood 2012;120:2954-62.

Douketis JD, Spyropoulos AC, Spencer FA, et al. Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141(2 Suppl):e326S-e350S.

Douketis JD, Berger PB, Dunn AS, et al. The perioperative management of antithrombotic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133(6 Suppl):299S-339S.

Vahanian A, Baumgartner H, Bax J, et al. Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European

Society of Cardiology. Eur Heart J 2007;28:230-68.




How to Cite

Chan TC, Tam AL, Wong VW, Lam BN. Antithrombotic treatment in ophthalmic surgery. Hong Kong J Ophthalmol [Internet]. 2018Sep.1 [cited 2023Dec.6];22(1):5-8. Available from:




Most read articles by the same author(s)