Optic nerve tortuosity associated with posterior staphyloma in high myopia: a case report

Authors

  • Ho Ming Lam Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China
  • Jasmine Clair Chuang 1. Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China. 2. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China
  • Carmen Kar Mun Chan 1. Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China. 2. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China
  • Hunter Kwok Lai Yuen 1. Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China. 2. Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China

Keywords:

Magnetic resonance imaging, Myopia, degenerative, Optic nerve

Abstract

We report on a case of bilateral tortuous optic nerve associated with posterior staphyloma and high myopia in a 50-year-old woman. Magnetic resonance imaging was used to evaluate potential etiologies. Posterior
staphyloma is the most likely etiology of bilateral tortuous optic nerve.

References

1. Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference. Arch Neurol 1988;45:575-8.

2. Ji J, Shimony J, Gao F, McKinstry RC, Gutmann DH. Optic nerve tortuosity in individuals with neurofibromatosis type 1. Pediatr Radiol 2013;43:1336-43.

3. DiMario FJ, Ramsby G, Greenstein R, Langshur S, Dunham B. Neurofibromatosis type 1: magnetic resonance imaging findings. J Child Neurol 1993;8:32-9.

4. Listernick R, Charrow J, Greenwald MJ, Esterly NB. Optic gliomas in children with neurofibromatosis type 1. J Pediatr 1989;114:788-92.

5. Armstrong GT, Localio AR, Feygin T, et al. Defining optic nerve tortuosity. Am J Neuroradiol 2007;28:666-71.

6. Wang MTM, Bhatti MT, Danesh-Meyer HV. Idiopathic intracranial hypertension: pathophysiology, diagnosis and management. J Clin Neurosci Off J Neurosurg Soc Australas 2022;95:172-9.

7. Basimah A, Faro SS, Yuan H, et al. Imaging hallmarks of idiopathic intracranial hypertension and insights into pathogenesis. Front Radiol 2025;5:1605777.

8. Kwee RM, Kwee TC. Systematic review and meta-analysis of MRI signs for diagnosis of idiopathic intracranial hypertension. Eur J Radiol 2019;116:106-15.

9. Pribojszki M, Komáromi K, Csomor A, Vörös E. Tortuous optic nerve. ECR 2017 EPOS. 1 March 2017. Accessed 20 October 2025. Available from: https://epos.myesr.org/poster/esr/ecr2017/C-2914

10. Pircher A, Berberat J, Remonda L, Roberts CJ, Neutzner A, Killer HE. Incidence of optic nerve kinking in a cohort of patients with Normal tension glaucoma. Eye (Lond) 2025; 39:1270-5.

11. Scott RA, Tarver WJ, Brunstetter TJ, Urquieta E. Optic nerve tortuosity on earth and in space. Aerosp Med Hum Perform 2020;91:91-7.

12. Curtin BJ. The posterior staphyloma of pathologic myopia. Trans Am Ophthalmol Soc 1977;75:67-86.

13. Ehongo A. Understanding posterior staphyloma in pathologic myopia: current overview, new input, and perspectives. Clin Ophthalmol 2023;17:3825-53.

14. Liu T, Wang YX, Jonas JB, Hoang QV, Girard MJA, Wang X. Gaze-induced optic nerve head deformations are greater in high myopia and strains increase with axial length. Invest Ophthalmol Vis Sci 2025;66:21.

15. Top Karti D, Karti O, Koç AM, Çelebisoy N. Optic nerve tortuosity in neurofibromatosis type 1: a rare case report. Neuroophthalmology 2020;45:313-6.

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Published

2026-04-10

How to Cite

1.
Lam HM, Chuang JC, Chan CKM, Yuen HKL. Optic nerve tortuosity associated with posterior staphyloma in high myopia: a case report. Hong Kong J Ophthalmol [Internet]. 2026 Apr. 10 [cited 2026 May 19];30(1). Available from: https://hkjo.hk/index.php/hkjo/article/view/416

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Section

Case Report

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