Ion transport mechanisms in the formation of aqueous humor

Authors

  • Chi-ho To Laboratory of Ocular Biochemistry and Physiology, Department of Optometry and Radiography, the Hong Kong Polytechnic University, Hong Kong.
  • Chi-wai Do Laboratory of Ocular Biochemistry and Physiology, Department of Optometry and Radiography, the Hong Kong Polytechnic University, Hong Kong.

Abstract

The aqueous humor dynamics of the eye are frequently associated with the vision-threatening disease, glaucoma. Pharmacological treatment for glaucoma generally aims to lower the intraocular pressure by reducing aqueous humor formation. Although the aqueous humor is believed to be actively secreted by the ciliary epithelium, the mechanism is still poorly understood. Many studies have been carried out in the last 40 years to unravel the underlying ionic mechanisms that drive aqueous humor formation. This review briefly surveys the ion transports in the ciliary epithelium, such as the possible roles of sodium, chloride and bicarbonate ions as the driving forces. It also examines the current ionic models for aqueous humor formation and its regulation from a cellular transport perspective.

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Published

1998-12-01

How to Cite

1.
To C- ho, Do C- wai. Ion transport mechanisms in the formation of aqueous humor. Hong Kong J Ophthalmol [Internet]. 1998Dec.1 [cited 2021Feb.27];2(1):35-42. Available from: https://hkjo.hk/index.php/hkjo/article/view/163

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Section

Review Articles