Laser in situ keratomileusis for anisometropia in adult patients

Abstract

Aims: To evaluate the visual and refractive results of laser in situ keratomileusis in adult patients with anisometropia, and to assess the predictability, safety, and efficacy of the procedure.

Patients and methods: 40 eyes of 25 patients aged 19 to 55 years with myopic anisometropia with or without astigmatism and amblyopia underwent laser in situ keratomileusis. Preoperative mean spherical and cylin- drical refraction was -11.70 ± 4.78 D (range, -3.75 to -22.00 D) and 1.98 ± 1.48 D (range, 0 to 6.00 D), respectively. The mean preoperative spherical and cylindrical refraction difference between the 2 eyes of each patient was 7.47 ± 3.76 D (range, 2.50 to 16.50 D) and 1.21 ± 1.44 D (range, 0 to 5.75D), respectively. Best spectacle-corrected visual acuity ranged from counting fingers to 20/20 (median, 20/30).

Results: Postoperatively, all eyes had reduced aniso- metropia. Spherical manifest refraction ranged from 1.50 to -11.00 D (mean -1.24 ± 2.02 D). Mean cylindrical refraction was 0.58 ± 0.62 D (range, 0 to 2.25 D). The mean spherical and cylindrical refraction difference between the 2 eyes of each patient was 1.49 ± 1.36 D (range, 0 to 5.75 D) and 0.65 ± 0.71 D (range, 0 to 2.25 D), respectively. Best spectacle-corrected visual acuity ranged from counting fingers to 20/20 (median, 20.0/ 22.5) postoperatively. Best spectacle-corrected visual acuity of 31 eyes (77.5%) increased by 1 to 7 lines. Among 22 amblyopic eyes, 14 eyes (63.6%) achieved 20/25 or 20/20. There were no significant complications following the procedure.

Conclusion: Laser in situ keratomileusis was safe, effective, and predictable for correction of anisometropia in adult patients.